MST® RESVERATROL: Supporting cellular metabolism and regulating aging processes

MST® Resveratrol 60 Capsules is a high-quality dietary supplement that you can buy in Germany and that is made in Germany (MADE IN GERMANY). It contains 150 mg of pure trans-resveratrol, derived from Japanese knotweed root extract (Japanese Knotweed Root Extract). This polyphenolic stilbenoid is the subject of intensive scientific research due to its key role in activating sirtuins (SIRT1) – enzymes involved in longevity and the regulation of cellular energy pathways [1.2, 1.7]. The product provides a concentrated dose of the active isomeric form required to maintain proper vascular system function and metabolic balance.

A closer look at trans-resveratrol and Japanese knotweed

Resveratrol is a powerful natural polyphenol belonging to the stilbenoid class. It exists in two isomeric forms – cis and trans, with trans-resveratrol recognized as the biologically active form that has a proven effect on cellular processes [2.3].

Japanese knotweed as a source of purity

Although resveratrol is mainly associated with red grapes and wine, the root extract of Japanese knotweed (Polygonum cuspidatum) is used to produce highly concentrated supplements such as MST® [1.2, 3.4].

• High concentration: Japanese knotweed root is one of the most reliable natural sources, providing a high concentration of trans-resveratrol (up to 98%) when commercially extracted [3.1, 3.7].

• Traditional use: In traditional Asian medicine, Polygonum cuspidatum extract has historically been used to support cardiovascular and respiratory function [1.4, 3.2].

The advantage of the trans form

MST® Resveratrol provides 150 mg of pure trans-resveratrol. Choosing this form is crucial, as its molecular structure ensures greater stability and effectiveness in interacting with key cellular targets involved in regulating cellular aging [1.3].

Fundamental mechanisms of action and SIRT1 activation

The scientific community pays special attention to resveratrol because of its unique ability to modulate fundamental signaling pathways associated with longevity and cellular resilience to stress.

Activation of "longevity regulators"

The key mechanism of action of trans-resveratrol is its role as an activator of Sirtuin 1 (SIRT1) [1.2, 1.7].

• SIRT1 is an NAD+-dependent protein deacetylase that acts as a central metabolic regulator [1.2].

• Activation of SIRT1 by the ingredient trans-resveratrol mimics the effects of calorie restriction, thereby increasing cell survival and regenerative capacity [1.2].

• By activating SIRT1, resveratrol promotes the expression of antioxidant genes (e.g., superoxide dismutase, catalase) via the Nrf2/ARE pathway and enhances cellular protection against oxidative damage [1.7].

Mitochondrial and energy function

SIRT1 activation also interacts with AMPK (AMP-activated protein kinase), which is crucial for:

• Mitochondrial biogenesis: Stimulates the formation of new mitochondria, the cell's energy centers. This helps maintain high energy output in cells, particularly in muscle and nerve tissues [1.5].

• Metabolic flexibility: Helps improve glucose transport and lipid balance in cells [1.5, 3.3].

Effects of the ingredient on vascular and metabolic functions

Studies have shown that regular intake of trans-resveratrol has a proven impact on the functional state of the circulatory system and metabolic processes.

Supporting the vascular system

• Endothelial function: Trans-resveratrol helps regulate eNOS (endothelial nitric oxide synthase), increasing the bioavailability of nitric oxide (•NO). This in turn promotes vasodilation (widening of the blood vessels) and helps maintain the elasticity of the vessel walls [1.7, 2.3].

• Cardioprotective effect: Improved endothelial function helps reduce the risk of atherosclerotic plaque formation and platelet aggregation, which is important for maintaining adequate blood flow and heart muscle function [2.3].

• Blood pressure: Meta-analyses of clinical studies suggest that taking trans-resveratrol at doses above 150 mg/day helps lower systolic and diastolic blood pressure in people with metabolic disorders [2.2].

Metabolic regulation

• Glycemic control: trans-resveratrol has been found to have a hypoglycemic effect at doses above 100 mg/day [1.5, 3.4]. This is due to its ability to increase insulin sensitivity and protect the pancreatic beta cells [3.2].

• Lipid profile: Clinical studies have observed that taking resveratrol helps lower LDL cholesterol levels (so-called "bad" cholesterol) [2.2, 3.4].

Benefits of the MST® formulation and 150 mg dosage

MST® Resveratrol is a highly pure product that ensures precise dosage of the active ingredient.

• Critical dosage: Each capsule contains 150 mg trans-resveratrol. This is the dose defined in clinical studies as the threshold for significant effects on vascular function and metabolic markers [2.2].

• Purity of the form: The use of Japanese knotweed root extract guarantees a high concentration of the trans-isomer, which is essential for SIRT1 activation and antioxidant protection [1.7].

• German quality (MADE IN GERMANY): Manufacturing in Germany guarantees compliance with strict European quality and purity standards.

Detailed overview of ingredients and dosage (per 1 capsule – daily dose)

The MST® Resveratrol formulation contains minimal excipients, focusing on the purity of the active ingredient.

Recommended intake for MST® Resveratrol

To achieve maximum effectiveness and consistency with the research protocols, it is important to follow the recommended dosage instructions.

Recommended dosage:

• Take 1 capsule daily.

  Directions for use:

• Take the capsule daily with plenty of water.

  Important information (EU-compliant):

1. Do not exceed the recommended daily intake.

2. This product is a dietary supplement and not a substitute for a complete, balanced diet.

3. Consult a specialist: People taking medication, especially anticoagulants or blood pressure medications, as well as pregnant or breastfeeding women, should consult a specialist before use.

4. Storage: Store in a cool, dry place, out of reach of small children.

Where to Buy MST® RESVERATROL: Availability in Germany and the EU

Purchase in the EU (European Union): MADE IN GERMANY

The MST® Resveratrol product, made in Germany, is widely available throughout Europe through MST Nutrition's distribution network. This guarantees premium quality and European standards of service.

If you want to buy high-quality trans-resveratrol at the best prices in Europe, choose official MST® products.

MST® Resveratrol is available in all major EU countries, including:

• Germany: Berlin, Munich, Hamburg.

• Poland: Warsaw, Krakow, Gdansk.

• France: Paris, Marseille, Lyon.

• Italy: Rome, Milan, Naples.

• Spain: Madrid, Barcelona, Valencia.

  For orders and detailed information, please visit the manufacturer's official German website:

• Official Manufacturer Website: Resveratrol 60 Capsules — Premium Quality

📚 Research Sources

[1.1] Resveratrol-like Compounds as SIRT1 Activators. ResearchGate, 2025.

[1.2] The role of sirtuin 1 and its activator, resveratrol in osteoarthritis. PMC, 2019.

[1.3] Mechanism of Human SIRT1 Activation by Resveratrol. ResearchGate, 2005.

[1.4] Resveratrol and SIRT1 Activators for the Treatment of Aging and Age-Related Diseases. ResearchGate, 2019.

[1.5] Effect of Resveratrol on Markers of Oxidative Stress and Sirtuin 1 in Elderly Adults with Type 2 Diabetes. NIH, 2023.

[1.7] Resveratrol-like Compounds as SIRT1 Activators. MDPI, 2022.

[2.2] Effect of Resveratrol on the Cardiovascular System. Encyclopedia.pub, 2021.

[2.3] Resveratrol and Cardiovascular Diseases. PMC, 2015.

[3.1] Bulk Polygonum Cuspidatum Extract (Trans-Resveratrol >20%). Ingredients Online.

[3.2] Polygonum cuspidatum – Knowledge and References. Taylor & Francis.

[3.3] Trans Resveratrol - Polygonum Cuspidatum. Hydra Longevity.

[3.4] A Comparative Evaluation of the Antioxidant Ability of Polygonum cuspidatum Extracts with That of Resveratrol Itself. MDPI, 2023.

[3.7] Polygonum Cuspidatum Extract 98% Trans Resveratrol. Phytochem International Inc.