MST® RESVERATROL: Supporting cellular metabolism and regulating aging processes

MST® Resveratrol 60 Capsules is a high-quality dietary supplement that you can buy in Germany and that was made in Germany (MADE IN GERMANY). It contains 150 mg of pure trans-resveratrol, obtained from Japanese knotweed root extract (Japanese Knotweed Root Extract). This polyphenolic stilbenoid is the subject of intensive scientific research due to its key role in activating sirtuins (SIRT1) – enzymes involved in longevity and the regulation of cellular energy pathways [1.2, 1.7]. The product provides a concentrated dose of the active isomeric form required to maintain the proper function of the vascular system and metabolic balance.

An in-depth look at trans-resveratrol and Japanese knotweed

Resveratrol is a powerful natural polyphenol belonging to the stilbenoid class. It exists in two isomeric forms – cis- and trans-, with trans-resveratrol recognized as the biologically active form that has demonstrated effects on cellular processes [2.3].

Japanese knotweed as a source of purity

Although resveratrol is primarily associated with red grapes and wine, the root extract of Japanese knotweed (Polygonum cuspidatum) is used to produce highly concentrated dietary supplements such as MST® [1.2, 3.4].

• High concentration: The root of Japanese knotweed is one of the most reliable natural sources and provides a high concentration of trans-resveratrol (up to 98%) when commercially extracted [3.1, 3.7].

• Traditional use: In traditional Asian medicine, Polygonum cuspidatum extract was historically used to support cardiovascular and respiratory functions [1.4, 3.2].

The advantage of the trans form

MST® Resveratrol provides 150 mg of pure trans-resveratrol. Choosing this form is crucial because its molecular structure ensures greater stability and efficacy when interacting with key target structures within the cell that play a role in regulating cellular aging [1.3].

Basic mechanisms of action and SIRT1 activation

The scientific community is paying particular attention to resveratrol because of its unique ability to modulate fundamental signaling pathways associated with longevity and cellular resistance to stress.

Activation of the "longevity regulators"

The key mechanism of action of trans-resveratrol is its function as an activator of sirtuin 1 (SIRT1) [1.2, 1.7].

• SIRT1 is an NAD+-dependent protein deacetylase that acts as a central metabolic regulator [1.2].

• Activation of SIRT1 by the ingredient trans-resveratrol mimics the effects of caloric restriction, thereby increasing cell survival and regenerative capacity [1.2].

• Through SIRT1 activation, resveratrol promotes the expression of antioxidant genes (e.g., superoxide dismutase, catalase) via the Nrf2/ARE pathway and strengthens cellular protection against oxidative damage [1.7].

Mitochondrial and energy function

SIRT1 activation also interacts with AMPK (AMP-activated protein kinase), which is crucial for the following:

• Mitochondrial biogenesis: Stimulates the formation of new mitochondria, which are the cell's energy centers. This helps maintain high cellular energy output, particularly in muscle and nerve tissues [1.5].

• Metabolic flexibility: Helps improve glucose transport and lipid balance in cells [1.5, 3.3].

Effect of the ingredient on vascular and metabolic functions

Studies have shown that regular intake of trans-resveratrol has a proven effect on the functional state of the circulatory system and metabolic processes.

Support for the vascular system

• Endothelial function: Trans-resveratrol helps regulate eNOS (endothelial nitric oxide synthase), increasing the bioavailability of nitric oxide (•NO). This in turn promotes vasodilation (widening of the blood vessels) and helps maintain the elasticity of the vessel walls [1.7, 2.3].

• Cardioprotective effect: Improved endothelial function helps reduce the risk of atherosclerotic plaque formation and platelet aggregation, which is important for maintaining adequate blood flow and heart muscle function [2.3].

• Blood pressure: Meta-analyses of clinical studies suggest that taking trans-resveratrol at doses above 150 mg/day helps lower systolic and diastolic blood pressure in people with metabolic disorders [2.2].

Metabolic regulation

• Glycemic control: It has been found that trans-resveratrol may have a hypoglycemic effect at doses above 100 mg/day [1.5, 3.4]. This is due to its ability to increase insulin sensitivity and protect the beta cells of the pancreas [3.2].

• Lipid profile: Clinical studies have observed that taking resveratrol contributes to reducing LDL cholesterol levels (the so-called "bad" cholesterol) [2.2, 3.4].

Benefits of the MST® formulation and 150 mg dosage

MST® Resveratrol is a high-purity product that ensures precise dosing of the active ingredient.

• Critical dosage: Each capsule contains 150 mg trans-resveratrol. This is the dose defined in clinical studies as the threshold for significant effects on vascular function and metabolic markers [2.2].

• Purity of the form: The use of Japanese knotweed root extract guarantees a high concentration of the trans-isomer, which is crucial for SIRT1 activation and antioxidant protection [1.7].

• German quality (MADE IN GERMANY): Manufacture in Germany guarantees compliance with strict European quality and purity standards.

Detailed overview of the ingredients and dosage (per 1 capsule - daily dose)

The MST® Resveratrol formulation contains minimal excipients, focusing on the purity of the active ingredient.

Consumption recommendations for MST® Resveratrol

To achieve maximum efficacy and consistency with the research protocols, it is important to follow the recommended dosage schedule.

Recommended dosage:

• Take 1 capsule daily.

  Dosage schedule:

• The capsule should be taken daily with sufficient water.

  Important information (EU-compliant):

1. The recommended daily intake must not be exceeded.

2. The product is a food supplement and not a substitute for a varied, balanced diet.

3. Consultation with a specialist: People taking medication, especially anticoagulants or blood pressure-regulating medications, as well as pregnant or breastfeeding women, should consult a specialist before use.

4. Storage: Store in a dry, cool place out of the reach of small children.

Where you can buy MST® RESVERATROL: Availability in Germany and the EU

Purchase in the EU (European Union): MADE IN GERMANY

The MST® Resveratrol product, manufactured in Germany, is widely available through the MST Nutrition distribution network in Europe. This guarantees Premium Quality and European Standards in service.

If you want to buy high-quality trans-resveratrol at the best prices in Europe, choose official MST® products.

MST® Resveratrol is available in all major EU countries, including:

• Germany (Germany): Berlin, Munich, Hamburg.

• Poland (Poland): Warsaw, Kraków, Gdańsk.

• France (France): Paris, Marseille, Lyon.

• Italy (Italy): Rome, Milan, Naples.

• Spain (Spain): Madrid, Barcelona, Valencia.

  For orders and detailed information, please visit the manufacturer's official German website:

• Official manufacturer's website: Resveratrol 60 Capsules — Premium Quality

📚 Research sources

[1.1] Resveratrol-like Compounds as SIRT1 Activators. ResearchGate, 2025.

[1.2] The role of sirtuin 1 and its activator, resveratrol in osteoarthritis. PMC, 2019.

[1.3] Mechanism of Human SIRT1 Activation by Resveratrol. ResearchGate, 2005.

[1.4] Resveratrol and SIRT1 Activators for the Treatment of Aging and Age-Related Diseases. ResearchGate, 2019.

[1.5] Effect of Resveratrol on Markers of Oxidative Stress and Sirtuin 1 in Elderly Adults with Type 2 Diabetes. NIH, 2023.

[1.7] Resveratrol-like Compounds as SIRT1 Activators. MDPI, 2022.

[2.2] Effect of Resveratrol on the Cardiovascular System. Encyclopedia.pub, 2021.

[2.3] Resveratrol and Cardiovascular Diseases. PMC, 2015.

[3.1] Bulk Polygonum Cuspidatum Extract (Trans-Resveratrol >20%). Ingredients Online.

[3.2] Polygonum cuspidatum – Knowledge and References. Taylor & Francis.

[3.3] Trans Resveratrol - Polygonum Cuspidatum. Hydra Longevity.

[3.4] A Comparative Evaluation of the Antioxidant Ability of Polygonum cuspidatum Extracts with That of Resveratrol Itself. MDPI, 2023.

[3.7] Polygonum Cuspidatum Extract 98% Trans Resveratrol. Phytochem International Inc.